Planning and Performance of Segment I, II and III Experiments: Practical Aspects and General Comments
作者： Helmut Sterz
DOI: 10.1007/978-3-642-77753-0_26
关键词:
摘要: In investigations on reproduction toxicology — as is also the case with other toxicity studies animals are used in place of man. However, if a hazard to be detected and risk for man assessed, then certain experimental conditions must fulfilled.
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sci-hub.st 参考文章(10)
Binder M, The teratogenic effects of a bis(dichloroacetyl)diamine on hamster embryos. Aortic arch anomalies and the pathogenesis of the DiGeorge syndrome. American Journal of Pathology. ,vol. 118, pp. 179- 193 ,(1985)
J.J. Amy, Methods in prenatal toxicology European Journal of Obstetrics & Gynecology and Reproductive Biology. ,vol. 9, pp. 281- ,(1979) , 10.1016/0028-2243(79)90069-8
James G. Wilson, Teratology : Principles and Techniques ,(1965)
R. E. Staples, J. K. Haseman, Selection of appropriate experimental units in teratology Teratology. ,vol. 9, pp. 259- 260 ,(1974) , 10.1002/TERA.1420090304
H. Sterz, H. Lehmann, A critical comparison of the freehand razor-blade dissection method according to Wilson with an in situ sectioning method for rat fetuses. Teratogenesis Carcinogenesis and Mutagenesis. ,vol. 5, pp. 347- 354 ,(1985) , 10.1002/TCM.1770050505
J. L. Stuckhardt, S. M. Poppe, Fresh visceral examination of rat and rabbit fetuses used in teratogenicity testing. Teratogenesis Carcinogenesis and Mutagenesis. ,vol. 4, pp. 181- 188 ,(1984) , 10.1002/TCM.1770040203
Mark V. Barrow, W. Jape Taylor, A rapid method for detecting malformations in rat fetuses Journal of Morphology. ,vol. 127, pp. 291- 305 ,(1969) , 10.1002/JMOR.1051270303
Charles Roux, Rolande Dupuis, Cécilia Horvath, Antoine Giroud, Interpretation of isolated agenesis of the pituitary Teratology. ,vol. 19, pp. 39- 43 ,(1979) , 10.1002/TERA.1420190107
J. G. Wilson, Methods for administering agents and detecting malformations in experimental animals Teratology. pp. 262- 277 ,(1965)
C. Bacchus, H. Sterz, W. Buselmaier, S. Sahai, H. Winking, Genesis and systematization of cardiovascular anomalies and analysis of skeletal malformations in murine trisomy 16 and 19. Two animal models for human trisomies. Human Genetics. ,vol. 77, pp. 12- 22 ,(1987) , 10.1007/BF00284706