Male genital tract inflammation: The role of selected interleukins in regulation of pro-oxidant and antioxidant enzymatic substances in seminal plasma.

摘要: Human semen contains spermatozoa as well populations of round nonspermatozoal cells primarily consisting leukocytes. Activation white blood present in the seminal plasma during genital tract inflammation and cellular reactions against microbial agents may provoke a release variety products such cytokines reactive oxygen species. The aim this study was to evaluate whether panel selected (interleukin [IL]-1 beta, IL-6, IL-8, tumor necrosis factor-alpha [TNF alpha]) detectable male could be considered mediators between altered parameters changed levels pro-oxidant antioxidant substances. Studies using chemiluminometric, spectrophotometric, enzyme-linked immunosorbent assay methods indicate that proinflammatory IL-1 TNF alpha modulate activities tract. data also suggest function systems directly influence basic parameters. elevated numbers leukocytes without an associated contribution capacity appear little prognostic value evaluating fertilization potential.