Periodic deworming with albendazole and its impact on growth status and diarrhoeal incidence among children in an urban slum of India.

作者: D. Sur , D.R. Saha , B. Manna , K. Rajendran , S.K. Bhattacharya

DOI: 10.1016/J.TRSTMH.2004.08.005

关键词:

摘要: This study was undertaken to measure the impact of periodic deworming with albendazole on growth status and incidence diarrhoea in children aged 2-5 years an urban setting India assess feasibility local health workers implementing procedures involved. a double-blind, placebo-controlled, randomized, community-based intervention trial 702 randomly allocated receive either or placebo. The two groups received doses (400 mg) placebo six months apart. Mean weight increased significantly group compared control at three months, nine following treatment (P<0.01, P<0.01 P<0.001 respectively). also experienced fewer episodes than their counterparts (relative risk 1.3, 95% CI 1.07-1.53) 28% reduction. administered correct dosage satisfactorily there were no adverse effects. Thus, mass would seem be safe effective method that could adopted community level as integral part school services expected improve reduce children.

参考文章(21)
Sukontason K, Na-Bangchang K, Piangjai S, Karbwang J, Successful eradication of Ascaris lumbricoides and hookworm infection after three repeated doses of albendazole. Journal of the Medical Association of Thailand Chotmaihet thangphaet. ,vol. 83, pp. 1095- ,(2000)
Sircar Bk, Sikder Sn, Saha Nc, Ghosh S, Saha Dr, Sengupta Pg, Mondal Sk, Gupta Dn, Intestinal parasitism: a childhood problem in rural Bengal. The Journal of communicable diseases. ,vol. 27, pp. 170- 174 ,(1995)
Robert H. Fletcher, Vinod Kumar Pande, Shally Awasthi, Effectiveness and cost-effectiveness of albendazole in improving nutritional status of pre-school children in urban slums. Indian Pediatrics. ,vol. 37, pp. 19- 29 ,(2000)
Ernesto Pollitt, William E. Watkins, Effect of removing Ascaris on the growth of Guatemalan schoolchildren. Pediatrics. ,vol. 97, pp. 871- 876 ,(1996)
Elizabeth J. Adams, Lani S. Stephenson, Michael C. Latham, Stephen N. Kinoti, Physical activity and growth of Kenyan school children with hookworm, Trichuris trichiura and Ascaris lumbricoides infections are improved after treatment with albendazole. Journal of Nutrition. ,vol. 124, pp. 1199- 1206 ,(1994) , 10.1093/JN/124.8.1199
Donald T. Simeon, Sally M. Grantham-McGregor, Joy E. Callender, Michael S. Wong, Treatment of Trichuris trichiura infections improves growth, spelling scores and school attendance in some children. Journal of Nutrition. ,vol. 125, pp. 1875- 1883 ,(1995) , 10.1093/JN/125.7.1875
Anne Pertet, Elizabeth J. Adams, Stephen N. Kinoti, Lani S. Stephenson, Michael C. Latham, Physical fitness, growth and appetite of Kenyan school boys with hookworm, Trichuris trichiura and Ascaris lumbricoides infections are improved four months after a single dose of albendazole. Journal of Nutrition. ,vol. 123, pp. 1036- 1046 ,(1993) , 10.1093/JN/123.6.1036
K H Young, S L Bullock, D M Melvin, C L Spruill, Ethyl acetate as a substitute for diethyl ether in the formalin-ether sedimentation technique. Journal of Clinical Microbiology. ,vol. 10, pp. 852- 853 ,(1979) , 10.1128/JCM.10.6.852-853.1979
Lon K. Kightlinger, J. Richard Seed, Mynna Boodhoo Kightlinger, Ascaris lumbricoides aggregation in relation to child growth status, delayed cutaneous hypersensitivity, and plant anthelmintic use in Madagascar. Journal of Parasitology. ,vol. 82, pp. 25- 33 ,(1996) , 10.2307/3284110
D L Pelletier, E A Frongillo, J P Habicht, Epidemiologic evidence for a potentiating effect of malnutrition on child mortality. American Journal of Public Health. ,vol. 83, pp. 1130- 1133 ,(1993) , 10.2105/AJPH.83.8.1130