A novel acquired inv(2)(p23.3q24.3) with concurrent submicroscopic deletions at 2p23.3, 2p22.1, 2q24.3 and 1p13.2 in a patient with chronic thrombocytopenia and anemia.

摘要: Background Thrombocytopenia can result from a wide range of conditions and may be determined by multiple mechanisms. It due to reduced platelet production or an increased destruction platelets. Increased is seen in such as disseminated intravascular coagulation (DIC) thrombotic microangiopathies, whereas decreased bone marrow (BM) failure syndromes aplastic anemia, myelodysplastic syndromes, chemotherapy-induced thrombocytopenia. In BM thrombocytopenia often accompanied anemia and/or leucopenia. Recognition the cause crucial for correct management patients.