The potency of newly development H5N8 and H9N2 avian influenza vaccines against the isolated strains in laying hens from Egypt during 2019
作者： Mohamed M. Soliman , Ahmed M. E. Hegazy , Hala M. N. Tolba , Mohamed.T. El-Saadony , Salama Mostafa Aboelenin
DOI: 10.1016/J.SJBS.2021.05.049
关键词:
摘要: Abstract Avian influenza (AI) is a respiratory disease complex syndrome recently recorded in vaccinated flocks causing high economic losses. This study aimed to prepare inactivated vaccine from isolated field strains [highly pathogenic avian (HPAI) (H5N8) and low (LPAI) (H9N2)] compare the efficiency of two experimental vaccines some commercial H5 H9N2 laying hens. The obtained results indicated that identified (H5N8 H9N2) were protected AI as compared H5N1, H5N3, vaccines, which showed protection level 80, 70, 90%, respectively, indicating efficacy for developed vaccines. In addition, it significantly improved the virus shedding, especially when used booster dose. given antibody titer higher than was reached 9.3 log2, 9.7log2 H5N8 significantly groups 3 4 at 2nd WPV, while 3rd significant difference with group only. HI log2 WPV 9. In conclusion, dose could elicit strong immunity single-dose
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