In vitro assessment of agave fructans (Agave salmiana) as prebiotics and immune system activators.
作者： L. Moreno-Vilet , M.H. Garcia-Hernandez , R.E. Delgado-Portales , N.E. Corral-Fernandez , N. Cortez-Espinosa
DOI: 10.1016/J.IJBIOMAC.2013.10.039
关键词:
摘要: The prebiotic effect of agave fructans (Agave salmiana) was evaluated through the growth two lactic acid bacterial (LAB) strains (Lactobacillus casei and Bifidobacterium lactis). immune system activated stimulation peripheral blood mononuclear cells (PBMC) healthy subjects testing fructans, LAB or a mixture these compounds at different concentrations. Immune responses, such as early cell activation (CD69), cycle progression, nitric oxide (NO) production expression transcription factors for lymphocyte differentiation, were analyzed. Compared with other extracted showed highest activity increased levels CD69 expression, proliferative NO when administered probiotic L. casei. Th1 differentiation produced greatly diminished after incorporation fructans. In conclusion, types (A. are involved in selective interactions probiotics. Thus, represent novel immunomodulator that might benefit functional food industry.
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