Cancer cells employ an evolutionarily conserved polyploidization program to resist therapy.
作者： K.J. Pienta , E.U. Hammarlund , R.H. Austin , R. Axelrod , J.S. Brown
DOI: 10.1016/J.SEMCANCER.2020.11.016
关键词:
摘要: … of cancer cells that enter a cell-state transition that includes 1) polyploidization of their aneuploid genome, and 2) exiting of the cell … cell size associated with WGD and the pause in cell …
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