Identification of novel antagonist toxins of t-type calcium channel for analgesic purposes

作者: Emmanuel Bourinet , Joël Nargeot , Michel Lazdunski , Pierre Escoubas , Fabrice Marger

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摘要: The invention relates to a peptide having the following sequence YCQKFLWTCDSERPCCEGLVCRLWCKIN (SEQ ID NO 1) or derivative thereof, and nucleic acids coding for 1). also use of this as an antagonist and/or reverse agonist T-type calcium channels. further preparing drug, in particular analgesic one.

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