ZAP-70 expression as a marker for chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL)
作者： Wyndham Wilson , Adrian Wiestner , Todd S. Barry , Andreas Rosenwald , Louis M. Staudt
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摘要: It has been surprisingly found that ZAP-70 expression, both at the protein and mRNA levels, is indicative of clinical subgroups CLL/SLL patients. In particular, high expression Ig-unmutated CLL/SLL. Methods are provided for discriminating between CLL/SLL, by determining whether subjects overexpress or protein.
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