Antibacterial effects of plant extracts with hurdle technology against Vibrio cholerae

摘要: Vibrio cholerae is an etiological cause of cholera implicated in several pandemics. Antibacterial activity plant extracts has been established. However, these exhibit at a concentration that may alter organoleptic attributes water and food, hence limiting their application. In this light, there need to device ways reducing extracts' effective levels order widen Thus, study was conducted improve activities ethanolic through combination with other generally recognized as safe antimicrobials. Combination sodium acetate (NaOAc) 0.4% pH 7.0 reduced minimum inhibitory concentrations (MICs) clove, lemon eucalyptus, rosemary sage from 0.2 0.025%. At 6.4, combinations were more MICs 0.0125% NaOAc 0.2%. 7.0, the resulted additive effect. Nevertheless, synergic effect No interactive observed involving glycine. mildly acidic creates hurdle have potential application control growth V. cholerae.