Genetic variation and its role in malignancy.
作者： Bente A. Talseth-Palmer , Rodney J. Scott
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摘要: Genetic variation has long been thought associated with common complex disease and therefore widely studied. in the human genome is present many forms have summarised this review. The potential role of DNA damage, repair environmental influence on genetic development cancer will be discussed, before significant projects are reviewed. All various malignancies extensively studied a review state field. We also discuss road ahead fulfilling ultimate goal all studies, which decreasing deaths caused by cancer.
ijbs.org 参考文章(230)
Shashi Bala, Päivi Peltomäki, CYCLIN D1 as a Genetic Modifier in Hereditary Nonpolyposis Colorectal Cancer Cancer Research. ,vol. 61, pp. 6042- 6045 ,(2001)
P M McKeigue, Mapping genes underlying ethnic differences in disease risk by linkage disequilibrium in recently admixed populations American Journal of Human Genetics. ,vol. 60, pp. 188- 196 ,(1997)
Timothy R. Rebbeck, María Elena Martínez, Peter G. Shields, John D. Potter, Christopher P. Wild, Thomas A. Sellers, Genetic variation and cancer: improving the environment for publication of association studies. Cancer Epidemiology, Biomarkers & Prevention. ,vol. 13, pp. 1985- 1986 ,(2004)
E. S. Lander, Genome-sequencing anniversary. The accelerator. Science. ,vol. 331, pp. 1024- ,(2011) , 10.1126/SCIENCE.1204037
Huettner Pc, Rader Js, Kamarasova T, Gerhard Ds, Li L, Li Y, Allelotyping of all chromosomal arms in invasive cervical cancer. Oncogene. ,vol. 13, pp. 2737- 2741 ,(1996)
Latchman Ds, Heat shock proteins and human disease. Journal of The Royal College of Physicians of London. ,vol. 25, pp. 295- ,(1991)
James F. Gusella, Marcy E. MacDonald, Huntington’s Disease Seminars in Cell Biology. ,vol. 6, pp. 21- 28 ,(1995) , 10.1016/1043-4682(95)90011-X
Raymonda Varon, Rebecca Gooding, Christina Steglich, Lorna Marns, Hua Tang, Dora Angelicheva, Kiau Kiun Yong, Petra Ambrugger, Anke Reinhold, Bharti Morar, Frank Baas, Marcel Kwa, Ivailo Tournev, Velina Guerguelcheva, Ivo Kremensky, Hanns Lochmüller, Andrea Müllner-Eidenböck, Luciano Merlini, Luitgard Neumann, Joachim Bürger, Maggie Walter, Kathryn Swoboda, P K Thomas, Arpad von Moers, Neil Risch, Luba Kalaydjieva, Partial deficiency of the C-terminal-domain phosphatase of RNA polymerase II is associated with congenital cataracts facial dysmorphism neuropathy syndrome. Nature Genetics. ,vol. 35, pp. 185- 189 ,(2003) , 10.1038/NG1243
David E Reich, Eric S Lander, On the allelic spectrum of human disease Trends in Genetics. ,vol. 17, pp. 502- 510 ,(2001) , 10.1016/S0168-9525(01)02410-6
A John Iafrate, Lars Feuk, Miguel N Rivera, Marc L Listewnik, Patricia K Donahoe, Ying Qi, Stephen W Scherer, Charles Lee, Detection of large-scale variation in the human genome. Nature Genetics. ,vol. 36, pp. 949- 951 ,(2004) , 10.1038/NG1416