Real-time monitoring of a photoactivated hydrogen persulfide donor for biological entities.

作者: Amrita Chaudhuri , Yarra Venkatesh , Bikash Chandra Jena , Krishna Kalyani Behara , Mahitosh Mandal

DOI: 10.1039/C9OB01982K

关键词:

摘要: Hydrogen persulfide (H2S2) plays an important role in sulfur-based redox signaling mechanisms. Herein, we developed a visible light activated ESIPT based H2S2 donor using a p-hydroxyphenacyl phototrigger. The unique feature of the designed H2S2 donor system is the ability to monitor the H2S2 release in real time through a non-invasive fluorescence color change approach, with the color changing from green to blue. Next, we demonstrated the detection and quantification of H2S2 using a fluorescein based “turn-on” fluorescent …

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