Relationship between Surface Properties and In Vitro Drug Release from a Compressed Matrix Containing an Amphiphilic Polymer Material.
作者： Cristhian J Yarce , Diego Pineda , Clara E Correa , Constain H Salamanca , None
DOI: 10.3390/PH9030034
关键词:
摘要: The performance of compressed tablet drug delivery systems made using polymeric materials depend on multiple factors, such as surface properties like contact angle, free energy and water absorption rate, besides the release mechanisms driven by kind polymer used. Hence, it should be possible to establish a relationship between kinetics. Compressed tablets with different proportions poly(maleic acid-alt-octadecene) potassium salt (0%, 10%, 20%, 30% 40%) were prepared. Blends model (ampicillin trihydrate) material analyzed DSC. determined sessile drop method, while was semi-empirical Young-Dupre, Neumann OWRK models. profiles simulating in vitro conditions (buffer solutions pH 1.2 7.4 ionic strength 1.5 M at 37 °C (310.15 K)). A kinetic analysis dissolution models (zero order, first Higuchi Korsmeyer-Peppas) realized. results showed significant effect proportion both release, indicating thermodynamic properties.
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sci-hub.se 参考文章(64)
C. Gamboa, A.F. Olea, Association of cationic surfactants to humic acid: Effect on the surface activity Colloids and Surfaces A: Physicochemical and Engineering Aspects. ,vol. 278, pp. 241- 245 ,(2006) , 10.1016/J.COLSURFA.2005.12.026
Moonchan Lee, Sanghee Lee, Changyong Yim, Sangmin Jeon, Surface wetting of superhydrophobic aluminum oxide nanostructures investigated using the fiber-optic spectrometer and quartz crystal microbalance Sensors and Actuators B-chemical. ,vol. 220, pp. 799- 804 ,(2015) , 10.1016/J.SNB.2015.05.134
Iman Hejazi, Gity Mir Mohamad Sadeghi, Seyed Hassan Jafari, Hossein Ali Khonakdar, Javad Seyfi, Matthias Holzschuh, Frank Simon, Transforming an intrinsically hydrophilic polymer to a robust self-cleaning superhydrophobic coating via carbon nanotube surface embedding Materials & Design. ,vol. 86, pp. 338- 346 ,(2015) , 10.1016/J.MATDES.2015.07.092
Loredana E. Nita, Aurica P. Chiriac, Liliana Mititelu-Tartau, Elena Stoleru, Florica Doroftei, Alina Diaconu, Patterning poly(maleic anhydride-co-3,9-divinyl-2,4,8,10-tetraoxaspiro (5.5) undecane) copolymer bioconjugates for controlled release of drugs International Journal of Pharmaceutics. ,vol. 493, pp. 328- 340 ,(2015) , 10.1016/J.IJPHARM.2015.07.061
Yevgeny Brudno, David J. Mooney, On-demand drug delivery from local depots. Journal of Controlled Release. ,vol. 219, pp. 8- 17 ,(2015) , 10.1016/J.JCONREL.2015.09.011
Hongmei Zhang, Jin Yang, Beibei Chen, Can Liu, Mingsuo Zhang, Changsheng Li, Fabrication of superhydrophobic textured steel surface for anti-corrosion and tribological properties Applied Surface Science. ,vol. 359, pp. 905- 910 ,(2015) , 10.1016/J.APSUSC.2015.10.191
Johanna Mosig, Peter Kleinebudde, Evaluation of lubrication methods: How to generate a comparable lubrication for dry granules and powder material for tableting processes Powder Technology. ,vol. 266, pp. 156- 166 ,(2014) , 10.1016/J.POWTEC.2014.06.022
A.C Zettlemoyer, V.V Subba Rao, Capabilities of the du Noüy Tensiometer Journal of Colloid and Interface Science. ,vol. 29, pp. 172- ,(1969) , 10.1016/0021-9797(69)90365-8
Marc Greiveldinger, Martin E.R. Shanahan, A Critique of the Mathematical Coherence of Acid/Base Interfacial Free Energy Theory Journal of Colloid and Interface Science. ,vol. 215, pp. 170- 178 ,(1999) , 10.1006/JCIS.1999.6259
C. Fürll, T. Hoffmann, The influence of the granulometric condition on the flow characteristics of shredded grain products in their dependence on the duration of storage Powder Technology. ,vol. 235, pp. 307- 311 ,(2013) , 10.1016/J.POWTEC.2012.10.040