Prochlorperazine-induced chronic cholestasis

作者: Anna SF Lok , Irene OL Ng , None

DOI: 10.1016/S0168-8278(88)80056-4

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摘要: Summary A patient with prochlorperazine-induced cholestasis that persisted for more than 2 years is reported. The timing of the onset jaundice, clinical, biochemical and histological findings subsequent course this were typical chlorpromazine-induced chronic cholestasis. Despite resolution liver biopsy performed after clinical disease showed fibrous expansion portal tracts focal porto-portal centro-portal bridging fibrosis, paucity inter-lobular bile ducts, a picture simulating primary biliary cirrhosis. Long-term follow-up required to determine whether will progress frank

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