Short- and long-term treatment of mouse cortical primary astrocytes with β-amyloid differentially regulates the mRNA expression of L-type calcium channels.

作者: Nina Daschil , Stefanie Geisler , Gerald J. Obermair , Christian Humpel

DOI: 10.1159/000357383

关键词:

摘要: Background: It is well established that reactive astrocytes express L-type calcium channels (LTCC), but their functional role completely unknown. We have recen

参考文章(32)
Nina Daschil, Gerald J. Obermair, Bernhard E. Flucher, Nadia Stefanova, Birgit Hutter-Paier, Manfred Windisch, Christian Humpel, Josef Marksteiner, CaV1.2 calcium channel expression in reactive astrocytes is associated with the formation of amyloid-β plaques in an Alzheimer's disease mouse model. Journal of Alzheimer's Disease. ,vol. 37, pp. 439- 451 ,(2013) , 10.3233/JAD-130560
Karma V. Moser, Christian Humpel, Blood-derived serum albumin contributes to neurodegeneration via astroglial stress fiber formation. Pharmacology. ,vol. 80, pp. 286- 292 ,(2007) , 10.1159/000106593
Jo Vandesompele, Katleen De Preter, Filip Pattyn, Bruce Poppe, Nadine Van Roy, Anne De Paepe, Frank Speleman, Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes Genome Biology. ,vol. 3, pp. 1- 12 ,(2002) , 10.1186/GB-2002-3-7-RESEARCH0034
Michael Willis, Walter A. Kaufmann, Georg Wietzorrek, Birgit Hutter-Paier, Sven Moosmang, Christian Humpel, Franz Hofmann, Manfred Windisch, Hans -Günther Knaus, Josef Marksteiner, L-type calcium channel CaV 1.2 in transgenic mice overexpressing human AbetaPP751 with the London (V717I) and Swedish (K670M/N671L) mutations. Journal of Alzheimer's Disease. ,vol. 20, pp. 1167- 1180 ,(2010) , 10.3233/JAD-2010-091117
B. MacVicar, Voltage-dependent calcium channels in glial cells Science. ,vol. 226, pp. 1345- 1347 ,(1984) , 10.1126/SCIENCE.6095454
Philip W. Landfield, Increased calcium-current hypothesis of brain aging Neurobiology of Aging. ,vol. 8, pp. 346- 347 ,(1987) , 10.1016/0197-4580(87)90074-1
Duane D. Hall, Monika A. Davare, Mei Shi, Margaret L. Allen, Michael Weisenhaus, G. Stanley McKnight, Johannes W. Hell, Critical Role of cAMP-dependent Protein Kinase Anchoring to the L-type Calcium Channel Cav1.2 via A-kinase Anchor Protein 150 in Neurons Biochemistry. ,vol. 46, pp. 1635- 1646 ,(2007) , 10.1021/BI062217X
Thomas J. Nelson, Changhai Cui, Yuan Luo, Daniel L. Alkon, Reduction of β-Amyloid Levels by Novel Protein Kinase Cϵ Activators Journal of Biological Chemistry. ,vol. 284, pp. 34514- 34521 ,(2009) , 10.1074/JBC.M109.016683
Isabelle Latour, Jawed Hamid, Aaron M. Beedle, Gerald W. Zamponi, Brian A. Macvicar, Expression of voltage-gated Ca2+ channel subtypes in cultured astrocytes Glia. ,vol. 41, pp. 347- 353 ,(2003) , 10.1002/GLIA.10162