Use of molecularly imprinted polymers from a mixture of tetracycline and its degradation products to produce affinity membranes for the removal of tetracycline from water.

摘要: Abstract The possibility of introducing multiple recognition in artificial receptors by imprinting polymers, using a mixture tetracycline (TC) and its degradation products as templates, has been examined. ability the resulting molecularly imprinted polymer (MIP), evaluated batch rebinding assay, was found to be group-specific tetracyclines, while single (MIP-2) prepared TC free from print molecule showed considerably high selectivity for doxycycline (DC) modest other derivatives, oxytetracycline (OTC) chlortetracycline (CTC). Based on property (MIP-1), applied affinity membrane extraction class-selective adsorption phase remove tetracyclines residues water. For this purpose, ground MIP incorporated plasticized poly(vinyl chloride)-membrane casting method. Affinity separation obtained analogs (CTC, OTC or DC) aqueous solutions dialysis exhibited significantly stronger towards structurally related compounds than “blank” having non-printed (NIP) phase. result these studies also indicates that drug saturating at receptor sites (deposited membrane) faster will released into chamber faster. These membranes were able extract water all pHs, highest being shown pH 7 feed solution, which gives lowest flux drug. Moreover, presence salt solution increases release bound membrane. results present study show simultaneous with formed situ template generates group polymeric material. High class fabricated receptor, together fast simple fabrication, provides good possibilities application processes antibiotics, often contaminate environment.