Colonization of porcine small intestine by Escherichia coli: ileal colonization and adhesion by pig enteropathogens that lack K88 antigen and by some acapsular mutants.

摘要: Seven K88-negative porcine enteropathogenic Escherichia coli, representing three different serogroups, caused severe diarrhea and characteristically colonized the ileum, but not jejunum, of intragastrically exposed newborn pigs. Bacterial counts intestinal contents wall, fluorescence, scanning electron microscopy all suggested that these strains ileum by adhesion to villous epithelium. However, in ligated loops, E. coli adhered jejunal epithelium as well ileal Acapsular (K-) mutants, derived from one principal strains, retained their colonizing adhesive abilities, whereas K- mutants other did not. It is that: (i) colonize adhesion, (ii) some K-88-negative mediated surface factors than, or addition to, polysaccharide K antigen.