Mitochondrial DNA polymorphisms, its copy number change and outcome in colorectal cancer
作者： Asan Meera Sahib Haja Mohideen , Elizabeth Dicks , Patrick Parfrey , Roger Green , Sevtap Savas
DOI: 10.1186/S13104-015-1250-5
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摘要: Background Mitochondrion is a small organelle inside the eukaryotic cells. It has its own genome (mtDNA) and encodes for proteins that are critical energy production cellular metabolism. Mitochondrial dysfunctions have been implicated in cancer progression may be related to poor prognosis patients. In this study we hypothesized genetic variations mtDNA associated with clinical outcome colorectal
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