NCI-60 Cell Line Screening: A Radical Departure in Its Time
作者： Bruce A. Chabner
DOI: 10.1093/JNCI/DJV388
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摘要: The year 2015 marked the 30th anniversary of National Cancer Institute's (NCI's) initial effort to establish a human cell line panel as basis for discovering new cancer drugs. At its inception, NCI-60 was controversial departure, born frustration with previous efforts that employed murine tumors and grounded in hope biology diverse somehow quite different than leukemia used 30 years. And while has not revolutionized drug discovery terms drugs resulted, it represents turning point philosophy practice research.
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sci-hub.se 参考文章(42)
J S Driscoll, The preclinical new drug research program of the National Cancer Institute. Cancer treatment reports. ,vol. 68, pp. 63- 76 ,(1984)
Bruce A. Chabner, Thomas G. Roberts, Chemotherapy and the war on cancer Nature Reviews Cancer. ,vol. 5, pp. 65- 72 ,(2005) , 10.1038/NRC1529
R.L. Bai, K.D. Paull, C.L. Herald, L. Malspeis, G.R. Pettit, E. Hamel, Halichondrin B and homohalichondrin B, marine natural products binding in the vinca domain of tubulin. Discovery of tubulin-based mechanism of action by analysis of differential cytotoxicity data. Journal of Biological Chemistry. ,vol. 266, pp. 15882- 15889 ,(1991) , 10.1016/S0021-9258(18)98491-7
Lisa A. Levin, Guillermo F. Mendoza, Benjamin M. Grupe, Jennifer P. Gonzalez, Brittany Jellison, Greg Rouse, Andrew R. Thurber, Anders Waren, Biodiversity on the Rocks: Macrofauna Inhabiting Authigenic Carbonate at Costa Rica Methane Seeps. PLOS ONE. ,vol. 10, ,(2015) , 10.1371/JOURNAL.PONE.0131080
Dominik Seelow, Raffaello Galli, Siegrun Mebus, Hans-Peter Sperling, Hans Lehrach, Silke Sperling, d-matrix – database exploration, visualization and analysis BMC Bioinformatics. ,vol. 5, pp. 168- 168 ,(2004) , 10.1186/1471-2105-5-168
William C. Reinhold, Margot Sunshine, Sudhir Varma, James H. Doroshow, Yves Pommier, Using CellMiner 1.6 for Systems Pharmacology and Genomic Analysis of the NCI-60 Clinical Cancer Research. ,vol. 21, pp. 3841- 3852 ,(2015) , 10.1158/1078-0432.CCR-15-0335
David M. Hyman, Igor Puzanov, Vivek Subbiah, Jason E. Faris, Ian Chau, Jean-Yves Blay, Jürgen Wolf, Noopur S. Raje, Eli L. Diamond, Antoine Hollebecque, Radj Gervais, Maria Elena Elez-Fernandez, Antoine Italiano, Ralf-Dieter Hofheinz, Manuel Hidalgo, Emily Chan, Martin Schuler, Susan Frances Lasserre, Martina Makrutzki, Florin Sirzen, Maria Luisa Veronese, Josep Tabernero, José Baselga, Vemurafenib in Multiple Nonmelanoma Cancers with BRAF V600 Mutations The New England Journal of Medicine. ,vol. 373, pp. 726- 736 ,(2015) , 10.1056/NEJMOA1502309
Yandisa Sikweyiya, Rachel Jewkes, Perceptions and Experiences of Research Participants on Gender-Based Violence Community Based Survey: Implications for Ethical Guidelines PLoS ONE. ,vol. 7, pp. e35495- ,(2012) , 10.1371/JOURNAL.PONE.0035495
Daniel Morgensztern, Meghan J Campo, Suzanne E Dahlberg, Robert C Doebele, Edward Garon, David E Gerber, Sarah B Goldberg, Peter S Hammerman, Rebecca S Heist, Thomas Hensing, Leora Horn, Suresh S Ramalingam, Charles M Rudin, Ravi Salgia, Lecia V Sequist, Alice T Shaw, George R Simon, Neeta Somaiah, David R Spigel, John Wrangle, David Johnson, Roy S Herbst, Paul Bunn, Ramaswamy Govindan, None, Molecularly targeted therapies in non-small-cell lung cancer annual update 2014 Journal of Thoracic Oncology. ,vol. 10, ,(2015) , 10.1097/JTO.0000000000000405
Alice T. Shaw, Sai-Hong I. Ou, Yung-Jue Bang, D. Ross Camidge, Benjamin J. Solomon, Ravi Salgia, Gregory J. Riely, Marileila Varella-Garcia, Geoffrey I. Shapiro, Daniel B. Costa, Robert C. Doebele, Long Phi Le, Zongli Zheng, Weiwei Tan, Patricia Stephenson, S. Martin Shreeve, Lesley M. Tye, James G. Christensen, Keith D. Wilner, Jeffrey W. Clark, A. John Iafrate, Crizotinib in ROS1-Rearranged Non–Small-Cell Lung Cancer The New England Journal of Medicine. ,vol. 371, pp. 1963- 1971 ,(2014) , 10.1056/NEJMOA1406766