Motor inhibition and cognitive flexibility in obsessive-compulsive disorder and trichotillomania.
作者： Barbara J. Sahakian , Samuel R. Chamberlain , Naomi A. Fineberg , Andrew D. Blackwell , Trevor W. Robbins
DOI: 10.1176/APPI.AJP.163.7.1282
关键词:
摘要: Objective: Problems with inhibiting certain pathological behaviors are integral to obsessive-compulsive disorder (OCD), trichotillomania, and other putative spectrum disorders. The authors assessed compared motor inhibition cognitive flexibility in OCD trichotillomania for the first time, their knowledge. Method: Stop-Signal Task Intradimensiona/Extradimensional Shift were administered 20 patients OCD, 17 healthy comparison subjects. Results: Both showed impaired of responses. For deficit was worse than degree correlated significantly symptom severity. Only deficits flexibility. Conclusions: Impaired responses (impulsivity) found whereas inflexibility (thought contribute compulsivity) limited OCD...
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