Treatment of refractory neurosarcoidosis with Infliximab

摘要: Background Neurological involvement in sarcoidosis is serious and often aggressive. Many patients respond to steroids but some show a progressive course despite treatment with even more potent immunosuppressive drugs. Objective The aim of this study was describe our experience the refractory neurosarcoidosis Infliximab—its effect on disease side effects. Methods A series four are reported combined various drugs whom Infliximab used. Results good response, improvement or stabilisation neurological condition, seen all cases, without significant chimeric monoclonal antibody that neutralises biological activity tumour necrosis factor α, cytokine thought play an important role pathophysiology sarcoidosis. Conclusion Our using adds growing evidence it may fulfil useful cases neurosarcoidosis.