Epigenetic Landscape Changes Due to Acupuncture Treatment: From Clinical to Basic Research.

摘要: Acupuncture has been widely used for treating diseases since the ancient days in China, but mechanism by which acupuncture exerts such powerful roles is unclear. Epigenetics, including DNA methylation, histone modification, and post-transcriptional regulation of miRNAs, study heritable changes gene expression that do not include sequence alterations. Epigenetics become a new strategy basic clinical research last decade. Some investigators have trying to illustrate from an epigenetics perspective, shed lights on mechanisms applications acupuncture. Moreover, introduction into regulatory treatment provided more objective scientific support theories brought opportunities improvement studies. In this paper, we reviewed literatures demonstrated could directly or indirectly affect epigenetics, order highlight progress studies correlated epigenetic regulations. We disclose current evidence review enough cover all complex interactions between multiple modifications their However, up-to-date results can help us better understand acupuncture's laboratory research.