作者: Bruce Beutler , Xin Du , Yu Xia
DOI: 10.1038/NI0707-659
关键词:
摘要: Mutations have been the driving force behind some of most important discoveries in immunology, and growing speed with which they can be found has impelled use random mutagenesis to create new immunological phenotypes mice. Here we describe how are created, detected ascribed genetic change.