Protein participating in the activation of nitrile hydratase and gene encoding the same

作者: Seiya Nikumaru , Kiyoshi Ito , Miyuki Tsuruoka , Tadashi Suzuki , Takeshi Nakamura

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摘要: The invention provides a nitrile hydratase activation protein participating in of derived from Pseudonocardia thermophila JCM3095, and gene sequence encoding the same. Further, recombinant plasmid containing gene, transformant strain obtained through transformation with plasmid, process for producing corresponding amide compound using culture solution cells by incubating treated products cells.

参考文章(5)
Michihiko Kobayashi, Sakayu Shimizu, Metalloenzyme nitrile hydratase: Structure, regulation, and application to biotechnology Nature Biotechnology. ,vol. 16, pp. 733- 736 ,(1998) , 10.1038/NBT0898-733
Yoshihiro Hashimoto*, Makoto Nishiyama, Sueharu Horinouchi, Teruhiko Beppu, Nitrile Hydratase Gene from Rhodococcus sp. N-774 Requirement for Its Downstream Region for Efficient Expression Bioscience, Biotechnology, and Biochemistry. ,vol. 58, pp. 1859- 1865 ,(1994) , 10.1271/BBB.58.1859
Mark Scott Payne, Robert Donald Fallon, Mark James Nelson, Nucleic acid fragments encoding stereospecific nitrile hydratase and amidase enzymes and recombinant microorganisms expressing those enzymes useful for the production of chiral amides and acides Official Gazette of the United States Patent and Trademark Office Patents. ,vol. 1214, pp. 4171- ,(1996)
Kiyoshi Ito, Miyuki Tsuruoka, Toshifumi Yakami, Takeshi Nakamura, Teruo Arii, Nitrile hydratase, derivatives thereof and methods of producing compounds ,(1997)
Miyuki Tsuruoka, 輝夫 有井, 利洋 及川, Teruo Arii, Toshibumi Yamaki, 俊文 八巻, みゆき 鶴岡, Toshihiro Oikawa, Production of amide compound with microorganism ,(1994)