作者: Andreas Kühbacher , Anke Burger-Kentischer , Steffen Rupp
DOI: 10.3390/MICROORGANISMS5020032
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摘要: The human skin is commonly colonized by diverse fungal species. Some Candida species, especially C. albicans, do not only reside on the surface as commensals, but also cause infections growing into tissue. However, defense mechanisms at barrier level are very efficient, involving residential non-immune and immune cells well specifically recruited to site of infection. Therefore, an effective against While most studies about commensal pathogenic interaction species with host epithelia focus mucosal surfaces such vaginal gastrointestinal epithelia, less known underlying skin. In this review, we ecology molecular pathogenesis give overview albicans in context. We discuss new research avenues dermal infection, including involvement neurons, fibroblasts, bacteria both mouse model systems.