Clindamycin/benzoyl peroxide gel (BenzaClin): a review of its use in the management of acne.

摘要: Abstract Clindamycin 1%/benzoyl peroxide 5% (BenzaClin®) is a combination gel indicated for use twice daily, or as directed by physician, the topical treatment of inflammatory and noninflammatory lesions acne vulgaris. In well designed clinical trials in patients with mild to moderately severe acne, efficacy once- twice-daily clindamycin/benzoyl reduction lesion counts was greater than that benzoyl alone, clindamycin tretinoin plus clindamycin, not significantly different from erythromycin/benzoyl peroxide. counts, but observed peroxide, Clindamycin/benzoyl has fairly rapid onset action, improvement usually recorded within 2–4 weeks. Despite widespread use, bacterial resistance associated The product generally tolerated, main treatment-related adverse events were application-site dryness, irritation, peeling, erythema. Thus, an effective tolerated option management acne.