Mechanism of acetate synthesis from CO2 by Clostridium acidiurici.

摘要: Total synthesis of acetate from CO2 by Clostridium acidiurici during fermentations hypoxanthine has been shown to involve glycine methylenetetrahydrofolate, CO2, and NH3. The is converted serine the addition resulting pyruvate, which decarboxylated form acetate. Since both carbons are derived CO2. evidence supporting this pathway based on (i) demonstration that decarboxylase present in C. acidiurici, (ii) fact synthesized crude extracts at a rate rapid enough account for vivo (iii) methylenetetrahydrofolate an intermediate formation (iv) alpha carbon source carboxyl group Evidence presented does not carboxylation methyl corrinoid enzyme such as occurs thermoaceticum formicoaceticum. Thus, there two different mechanisms total clostridia.