High-Dose Chemotherapy/Stem Cell Transplantation (HDSCT)

摘要: The treatment of most brain malignancies is a challenge and rather daunting task given the general poor outcomes seen within this population children. mainstay has been remains aggressive complete surgical resection even consideration second-look surgery to achieve goal. In malignancies, use radiation imperative but associated with significant long-term deficits especially in younger child. chemotherapy emerged as strong modality improve well delay omit part treatment. For tumors that show favorable response chemotherapy, it speculated using high-dose obtain reasonable dose intensity may further outcomes. This chapter discusses approach for specific aims guide reader where be beneficial.