Analysis of circulating DNA and protein biomarkers to predict the clinical activity of regorafenib and assess prognosis in patients with metastatic colorectal cancer: a retrospective, exploratory analysis of the CORRECT trial

作者: Josep Tabernero , Heinz-Josef Lenz , Salvatore Siena , Alberto Sobrero , Alfredo Falcone

DOI: 10.1016/S1470-2045(15)00138-2

关键词:

摘要: … We selected the genes that were analysed for mutations in this study (KRAS, BRAF, and PIK3CA) on the basis of evidence of their potential predictive value, and on their high mutation …

参考文章(48)
Frank Diehl, Meng Li, Yiping He, Kenneth W Kinzler, Bert Vogelstein, Devin Dressman, BEAMing: single-molecule PCR on microparticles in water-in-oil emulsions Nature Methods. ,vol. 3, pp. 551- 559 ,(2006) , 10.1038/NMETH898
Andrea Sottoriva, Haeyoun Kang, Zhicheng Ma, Trevor A Graham, Matthew P Salomon, Junsong Zhao, Paul Marjoram, Kimberly Siegmund, Michael F Press, Darryl Shibata, Christina Curtis, None, A Big Bang model of human colorectal tumor growth Nature Genetics. ,vol. 47, pp. 209- 216 ,(2015) , 10.1038/NG.3214
Lee M. Ellis, Daniel J. Hicklin, VEGF-targeted therapy: mechanisms of anti-tumour activity Nature Reviews Cancer. ,vol. 8, pp. 579- 591 ,(2008) , 10.1038/NRC2403
M. FRATTINI, G. GALLINO, S. SIGNORONI, D. BALESTRA, L. BATTAGLIA, G. SOZZI, E. LEO, S. PILOTTI, M. A PIEROTTI, Quantitative analysis of plasma DNA in colorectal cancer patients: a novel prognostic tool. Annals of the New York Academy of Sciences. ,vol. 1075, pp. 185- 190 ,(2006) , 10.1196/ANNALS.1368.025
Yan Ning, Heinz-Josef Lenz, Targeting IL-8 in colorectal cancer Expert Opinion on Therapeutic Targets. ,vol. 16, pp. 491- 497 ,(2012) , 10.1517/14728222.2012.677440
L Paré-Brunet, A Sebio, J Salazar, A Berenguer-Llergo, E Río, A Barnadas, M Baiget, D Páez, Genetic variations in the VEGF pathway as prognostic factors in metastatic colorectal cancer patients treated with oxaliplatin-based chemotherapy. Pharmacogenomics Journal. ,vol. 15, pp. 397- 404 ,(2015) , 10.1038/TPJ.2015.1
Chan Yong Sung, Myoung Won Son, Tae Sung Ahn, Dong Jun Jung, Moon Soo Lee, Moo Jun Baek, Expression of placenta growth factor in colorectal carcinomas. Journal of The Korean Society of Coloproctology. ,vol. 28, pp. 315- 320 ,(2012) , 10.3393/JKSC.2012.28.6.315
Frank Diehl, Kerstin Schmidt, Michael A Choti, Katharine Romans, Steven Goodman, Meng Li, Katherine Thornton, Nishant Agrawal, Lori Sokoll, Steve A Szabo, Kenneth W Kinzler, Bert Vogelstein, Luis A Diaz Jr, Circulating mutant DNA to assess tumor dynamics Nature Medicine. ,vol. 14, pp. 985- 990 ,(2008) , 10.1038/NM.1789
Matija Snuderl, Ana Batista, Nathaniel D Kirkpatrick, Carmen Ruiz de Almodovar, Lars Riedemann, Elisa C Walsh, Rachel Anolik, Yuhui Huang, John D Martin, Walid Kamoun, Ellen Knevels, Thomas Schmidt, Christian T Farrar, Benjamin J Vakoc, Nishant Mohan, Euiheon Chung, Sylvie Roberge, Teresa Peterson, Carlos Bais, Boryana H Zhelyazkova, Stephen Yip, Martin Hasselblatt, Claudia Rossig, Elisabeth Niemeyer, Napoleone Ferrara, Michael Klagsbrun, Dan G Duda, Dai Fukumura, Lei Xu, Peter Carmeliet, Rakesh K Jain, None, Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma. Cell. ,vol. 152, pp. 1065- 1076 ,(2013) , 10.1016/J.CELL.2013.01.036
Jolien Tol, Iris D. Nagtegaal, Cornelis J.A. Punt, BRAF mutation in metastatic colorectal cancer. The New England Journal of Medicine. ,vol. 361, pp. 98- 99 ,(2009) , 10.1056/NEJMC0904160