Handbook of glycomics

摘要: This handbook provides the first comprehensive overview of emerging field glycomics, defined as study all complex carbohydrates in an organism or cell ("the glycome"). Beginning with analytic approaches and bioinformatics, this work a detailed discussion relevant databases, data integration, analysis. It then moves on to specific model pathogen glycomes followed by therapeutic human disorders glycosylization. Structure function are included along state-of-the-art technologies systems analysis glycans. * Synthesizes contributions from experts biology, chemistry, biotechnology, medicine Highlights chapters devoted chemical synthesis, cancer glycomics immune Includes discussions proteomics, mass spectrometry, NMR, array technology, transcriptomics