Antiretroviral Drugs During Breastfeeding for the Prevention of Postnatal Transmission of HIV-1

摘要: The global pediatric human immunodeficiency virus (HIV) type 1 epidemic is fueled to a large extent by postnatal transmission from mother infant through breastfeeding. As many as 90% of the estimated 430,000 new HIV infections in children less than 15 years age 2008 were due mother-to-child (MTCT) [1]. MTCT can occur utero, intrapartum, or postpartum breastfeeding; among with known timing infection, much 30–40% HIV-1 attributable this proportion may be even higher settings where effective interventions that decrease utero and intrapartum are being implemented [2–4].