Potential impact of new WHO criteria for antiretroviral treatment for prevention of mother-to-child HIV transmission

作者: Louise Kuhn , Grace M Aldrovandi , Moses Sinkala , Chipepo Kankasa , Mwiya Mwiya

DOI: 10.1097/QAD.0B013E3283394F5B

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摘要: We reviewed the potential impact of new World Health Organization criteria for antiretroviral therapy using data from 1025 HIV-infected women and infants followed through 24 months in Lusaka, Zambia. The require initiating among 68% pregnant and, if fully effective, would prevent 92% maternal deaths 88% perinatal postnatal infections. Using CD4 <350 cells/uL, irrespective clinical stage, is more efficient stricter cut-offs be counter-productive.

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