MAINTENANCE OF THERAPEUTIC EFFECTS OF TOTAL SLEEP-DEPRIVATION BY LIMITATION OF SUBSEQUENT SLEEP - A PILOT-STUDY

摘要: In a previous study it was shown that in endogenous depression repeated sleep deprivation (SD) during clomipramine treatment resulted rapid improvement after each SD. However, except the first night, relapses were observed all nights following SD (the "recovery nights"). The present pilot had therapeutic aim, namely to prevent these relapses. We interested whether limitation of recovery might and different amounts would have effects on course mood sleep. Ten endogenously depressed patients treated with three SD's. Five slept for approximately 2 h, other five about 5 h second third nights. On average, no relapse by and, fact, there some additional nights, contrast findings study, where allowed unlimited