作者: Lydia A. Trupe , Daniel D. Varma , Yessenia Gomez , David Race , Richard Leigh
DOI: 10.1161/STROKEAHA.112.678508
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摘要: Background and Purpose— Apraxia of speech (AOS) is an impairment motor planning programming articulation often considered important stroke syndrome, localizable to Broca’s area. However, influential study raised doubts on this localization reported that AOS attributable lesions the anterior insula, based association between chronic insula lesions. We hypothesized associated with large (which include insula) or Method— tested 34 participants left supratentorial battery obtained concurrent magnetic resonance imaging. evaluated associations locations volume infarct. Results— The presence (n=17) was infarct, but also infarct in area (and several other regions, not both volume- age-adjusted linear regression dichotomous analysis. Carotid dissection more common, cardioembolism less as a cause patients compared those without. Severity strongly lesion volume. Conclusions— Persistence after 12 months hemispheric strokes involve relatively areas which it structurally functionally connected. Patients such may benefit from early training use technologies support production communication.