International Union of Basic and Clinical Pharmacology. C. Nomenclature and Properties of Calcium-Activated and Sodium-Activated Potassium Channels

作者: Leonard K. Kaczmarek , Richard W. Aldrich , K. George Chandy , Stephan Grissmer , Aguan D. Wei

DOI: 10.1124/PR.116.012864

关键词:

摘要: A subset of potassium channels is regulated primarily by changes in the cytoplasmic concentration ions, including calcium, sodium, chloride, and protons. The eight members this subfamily were originally all designated as calcium-activated channels. More recent studies have clarified gating mechanisms for these documented that not are sensitive to calcium. This article describes molecular relationships between provides an introduction their functional properties. It also introduces a new nomenclature differentiates calcium- sodium-activated

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