Bioactive Antimicrobial Peptides as Therapeutics for Corneal Wounds and Infections.
作者： Gina L. Griffith , Anne Kasus-Jacobi , H. Anne Pereira
关键词:
摘要: Significance: More than 2 million eye injuries and infections occur each year in the United States that leave civilians military members with reduced or complete vision loss due to lack of effective therapeutics. Severe ocular varied settings including home, workplace, battlefields. In this review, we discuss potential developing antimicrobial peptides (AMPs) as therapeutics for treatment corneal wounds which current options are inadequate. Recent Advances: Standard-of-care employs use fluorescein dye diagnosis defects is followed by antibiotics and/or steroids treat infection reduce inflammation. advances treating include development amniotic membrane therapies, wound chambers, drug-loaded hydrogels. will an innovative approach using AMPs dual effect promoting healing and...
sci-hub.se 参考文章(92)
N L Burstein, R R Pfister, The normal and abnormal human corneal epithelial surface: a scanning electron microscope study. Investigative Ophthalmology & Visual Science. ,vol. 16, pp. 614- 622 ,(1977)
John G. Morgan, H. Anne Pereira, Teresa Sukiennicki, John K. Spitznagel, James W. Larrick, Human neutrophil granule cationic protein CAP37 is a specific macrophage chemotaxin that shares homology with inflammatory proteinases. Advances in Experimental Medicine and Biology. ,vol. 305, pp. 89- 96 ,(1991) , 10.1007/978-1-4684-6009-4_11
Lars Steinstraesser, Till Koehler, Frank Jacobsen, Adrien Daigeler, Ole Goertz, Stefan Langer, Marco Kesting, Hans Steinau, Elof Eriksson, Tobias Hirsch, Host defense peptides in wound healing. Molecular Medicine. ,vol. 14, pp. 528- 537 ,(2008) , 10.2119/2008-00002.STEINSTRAESSER
I K Gipson, M Keough, S Spurr-Michaud, A Tisdale, Reassembly of the anchoring structures of the corneal epithelium during wound repair in the rabbit. Investigative Ophthalmology & Visual Science. ,vol. 30, pp. 425- 434 ,(1989)
Michelle C. Callegan, James Chodosh, Michael S. Gilmore, Mary C. Booth, H. Anne Pereira, Xin Ruan, Taunia D. Lee, Padmasini Kumar, Corneal expression of the inflammatory mediator CAP37. Investigative Ophthalmology & Visual Science. ,vol. 43, pp. 1414- 1421 ,(2002)
Steven E Wilson, Woo-Jung Kim, None, Keratocyte apoptosis: implications on corneal wound healing, tissue organization, and disease. Investigative Ophthalmology & Visual Science. ,vol. 39, pp. 220- 226 ,(1998)
Alison M. McDermott, The Role of Antimicrobial Peptides at the Ocular Surface Ophthalmic Research. ,vol. 41, pp. 60- 75 ,(2009) , 10.1159/000187622
J L Snable, C G Wilde, R W Scott, M N Marra, J E Griffith, Bactericidal/permeability-increasing protein has endotoxin-neutralizing activity. Journal of Immunology. ,vol. 144, pp. 662- 666 ,(1990)
Mark D P Willcox, Review of resistance of ocular isolates of Pseudomonas aeruginosa and staphylococci from keratitis to ciprofloxacin, gentamicin and cephalosporins. Clinical and Experimental Optometry. ,vol. 94, pp. 161- 168 ,(2011) , 10.1111/J.1444-0938.2010.00536.X
Robert N. Lausch, John E. Oakes, Christopher L. Cubitt, Synthesis of type II interleukin-1 receptors by human corneal epithelial cells but not by keratocytes Investigative Ophthalmology & Visual Science. ,vol. 42, pp. 701- 704 ,(2001)