Circulating Endothelial-Derived Activated Microparticle: A Useful Biomarker for Predicting One-Year Mortality in Patients with Advanced Non-Small Cell Lung Cancer
作者： Chin-Chou Wang , Chia-Cheng Tseng , Chang-Chun Hsiao , Huang-Chih Chang , Li-Teh Chang
DOI: 10.1155/2014/173401
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摘要: Background. This study tested the hypothesis that circulating microparticles (MPs) are useful biomarkers for predicting one-year mortality in patients with end-stage non-small cell lung cancer (ES-NSCLC). Methods and Results. One hundred seven patients were prospectively enrolled into the study between April 2011 and February 2012, and each patient received regular follow-up after enrollment. Levels of four MPs in circulation,(1) platelet-derived activated MPs (PDAc-MPs),(2) platelet-derived apoptotic MPs (PDAp-MPs),(3) endothelial …
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