Participation in biomedical research: The consent process as viewed by children, adolescents, young adults, and physicians

摘要: We examined the capacity of children, adolescents, and young adults to assent consent participation in biomedical research, what physician-investigators believe is important for patients these age groups know about such participation. The sample included 44 male female subjects, ranging from 7 20 years, who were hospitalized treat elther pediatric cancer or obesity. participants completed a structured interview that assessed knowledge research using elements outlined federal guidelines informed consent. study subjects most knowledgeable those concrete information (e.g., freedom ask questions, time involved, benefits participation). They less abstract scientific vs therapeutic purpose study, alternative treatments). Chronologic was not related strategies used reason appeared parallel their reasoning other physical phenomena.