Assay of urokinase activity in plasma with a chromogenic substrate

摘要: Abstract Plasma urokinase(UK) activity was measured using synthetic substrate(S-2444, Kabi) and aprotinin. The factors which were necessary for retention of UK during administration examined. suitable concentration aprotinin did not suppress the on S-2444 inhibited plasmin as well decrease in plasminogen activation, 10 KIU/ml. When infused at a speed 12×10 4 IU/hr hours, appeared after 2 hours increased to 75 IU/ml hours. α -plasmin inhibitor decreased 57% reached 39% These results suggest that regulated mainly by level -PI began appear when fell below about 50%.