Prevalence Soil Transmitted Helminthiasis and malaria co-infection among pregnant women and risk factors in Gilgel Gibe dam Area, Southwest Ethiopia

作者: Million Getachew , Ketema Tafess , Ahmed Zeynudin , Delenesaw Yewhalaw

DOI: 10.1186/1756-0500-6-263

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摘要: Malaria and Soil Transmitted Helminthiasis (STH) are co-endemic major public health problems in Ethiopia. The aim of the study was to assess prevalence malaria STHs co-infection determine association risk factors. A cross-sectional community based conducted on 388 pregnant women living three districts around Gilgel Gibe Dam area, southwestern Socio-demographic socio-economic data, single stool sample blood were collected from each participant. STH 159 (41%) 45 (11.6%), respectively STHs/malaria 30 (7.7%). Hookworm most prevalent 114 (29.4%) soil transmitted helminthiasis infection followed by Ascaris lumbricoides (A. lumbricoides) 58 (15%) Trichuris trichiura (T. trichiura) 13 (3.4%). Habit eating (Adjusted Odds Ratio (AOR) = 4.64, 95% CI: 1.50-14.36, P=0.008), presence stagnant water near participants’ house (AOR=2.99, 1.28-6.99, P=0.012) habit using human feces as a fertilizer (AOR= 5.34, 1.99-14.28, P<0.001) found be significantly associated with among women. parasitic load positively correlated (r 0.299, while A. negatively −0.095, P<0.001). Intestinal parasite and/or is problem dam area. Therefore, intervention including improving sanitation, removing water, education should given.

参考文章(22)
E. M. Riley, I. Sambou, B. M. Greenwood, G. Schneider, Suppression of cell-mediated immune responses to malaria antigens in pregnant Gambian women. American Journal of Tropical Medicine and Hygiene. ,vol. 40, pp. 141- 144 ,(1989) , 10.4269/AJTMH.1989.40.141
Nelly J. Yatich, Julian C. Rayner, Archer Turpin, Pauline E. Jolly, William O. Ellis, Jonathan K. Stiles, Tsiri Agbenyega, John E. Ehiri, Ellen Funkhouser, Jonathan H. Williams, Jiang Yi, Malaria and intestinal helminth co-infection among pregnant women in Ghana: prevalence and risk factors. American Journal of Tropical Medicine and Hygiene. ,vol. 80, pp. 896- 901 ,(2009) , 10.4269/AJTMH.2009.80.896
AO Egwunyenga, JA Ajayi, OPG Nmorsi, DD Duhlinska-Popova, Plasmodium/intestinal helminth co-infections among pregnant Nigerian women. Memorias Do Instituto Oswaldo Cruz. ,vol. 96, pp. 1055- 1059 ,(2001) , 10.1590/S0074-02762001000800005
Machteld Boel, Verena I. Carrara, Marcus Rijken, Stephane Proux, Mathieu Nacher, Mupawjay Pimanpanarak, Moo Koo Paw, Oh Moo, Hser Gay, Wendi Bailey, Pratap Singhasivanon, Nicholas J. White, François Nosten, Rose McGready, Complex Interactions between Soil-Transmitted Helminths and Malaria in Pregnant Women on the Thai-Burmese Border PLoS Neglected Tropical Diseases. ,vol. 4, pp. e887- ,(2010) , 10.1371/JOURNAL.PNTD.0000887
T. W. Mwangi, J. M. Bethony, S. Brooker, Malaria and helminth interactions in humans: an epidemiological viewpoint Annals of Tropical Medicine and Parasitology. ,vol. 100, pp. 551- 570 ,(2006) , 10.1179/136485906X118468
F. C. HARTGERS, M. YAZDANBAKHSH, Co-infection of helminths and malaria: modulation of the immune responses to malaria. Parasite Immunology. ,vol. 28, pp. 497- 506 ,(2006) , 10.1111/J.1365-3024.2006.00901.X
Brown J. Okoko, G. Enwere, M.O.C. Ota, The epidemiology and consequences of maternal malaria: a review of immunological basis Acta Tropica. ,vol. 87, pp. 193- 205 ,(2003) , 10.1016/S0001-706X(03)00097-4
John Trowsdale, Alexander G Betz, Mother's little helpers: mechanisms of maternal-fetal tolerance Nature Immunology. ,vol. 7, pp. 241- 246 ,(2006) , 10.1038/NI1317
Zerihun Tadesse, Afework Hailemariam, Jan H. Kolaczinski, Potential for integrated control of neglected tropical diseases in Ethiopia. Transactions of The Royal Society of Tropical Medicine and Hygiene. ,vol. 102, pp. 213- 214 ,(2008) , 10.1016/J.TRSTMH.2007.09.005
Abraham Degarege, Abebe Animut, Mengistu Legesse, Berhanu Erko, Malaria and helminth co-infections in outpatients of Alaba Kulito Health Center, southern Ethiopia: a cross sectional study BMC Research Notes. ,vol. 3, pp. 143- 143 ,(2010) , 10.1186/1756-0500-3-143