Pattern of Plasmodium-intestinal helminth co-infection among pregnant women in a high transmission zone of malaria in Nigeria

作者: Olarewaju Abdulkareem Babamale , Olalere Shittu , Yusuf Kanya Danladi , Jimoh Yemi Abdulraheem , Uade Samuel Ugbomoiko

DOI: 10.1016/S2222-1808(16)61060-5

关键词: GestationPlasmodium falciparumVeterinary medicineMass drug administrationMalariaHelminthsTransmission (medicine)PregnancyAscaris lumbricoidesObstetricsMedicine

摘要: Abstract Objective To investigate the co-infection of malaria and intestinal helminths its burden among pregnant women in Kwara State, Nigeria. Methods Blood faecal samples were randomly examined using blood smear Kato-Katz techniques, respectively. Micro-haematocrit reader was used to estimate packed cell volume (PCV) while information concerning pregnancy transmission factors obtained by questionnaire. Results Out 300 women, 17.3% had at least one parasite infection specific rate 73.1%. Co-infection Plasmodium falciparum Ascaris lumbricoides decreased with increasing age concurrence hookworm increased women. It observed that helminth protected severity aggravated anaemia level. Pregnant alone average parasitaemia 1 034.9 parasite/μL PCV 30.24% individuals co-infected hookworms 859.67 26.98%. Our findings also indicated prevalence varied gestation periods. The highest recorded their primigravidae first trimester. Inadequate toilet facilities, illiteracy, occupations, low incomes proximities vegetation around habitation influence multiple parasites. Conclusions Mass drug administration maintenance personal environmental hygiene are essential preventive measures endemic communities ward off debilitating effects parasites pregnancy.

参考文章(34)
J. Haidar, H. Nekatibeb, K. Urga, Iron Deficiency Anaemia in Pregnant and Lactating Mothers in Rural Ethiopia East African Medical Journal. ,vol. 76, pp. 618- 622 ,(1999)
CO Falade, OG Ademowo, O Olayemi, CO Aimakhu, LA Salako, HO Dada-Adegbola, Prevalence of malaria at booking among antenatal clients in a secondary health care facility in Ibadan, Nigeria African Journal of Reproductive Health. ,vol. 12, pp. 141- 152 ,(2008) , 10.4314/AJRH.V12I2.7867
Joël Ladner, Philippe Van De Perre, Etienne Karita, François Dabis, Joseph Bogaerts, Valériane Leroy, André De Clercq, Arlette Simonon, , HIV infection, malaria, and pregnancy: a prospective cohort study in Kigali, Rwanda. American Journal of Tropical Medicine and Hygiene. ,vol. 66, pp. 56- 60 ,(2002) , 10.4269/AJTMH.2002.66.56
Aurélie A. Righetti, Dominik Glinz, Lukas G. Adiossan, Ahou-Yah G. Koua, Sébastien Niamké, Richard F. Hurrell, Rita Wegmüller, Eliézer K. N'Goran, Jürg Utzinger, Interactions and Potential Implications of Plasmodium falciparum-Hookworm Coinfection in Different Age Groups in South-Central Côte d'Ivoire PLoS Neglected Tropical Diseases. ,vol. 6, pp. e1889- ,(2012) , 10.1371/JOURNAL.PNTD.0001889
Ayola A. Adegnika, Peter G. Kremsner, Epidemiology of malaria and helminth interaction: a review from 2001 to 2011. Current Opinion in Hiv and Aids. ,vol. 7, pp. 221- 224 ,(2012) , 10.1097/COH.0B013E3283524D90
Roy Douglas Pearson, Parasites, pregnancy, prolactin and pandemics? Trends in Parasitology. ,vol. 21, pp. 555- 556 ,(2005) , 10.1016/J.PT.2005.09.001
T. W. Mwangi, J. M. Bethony, S. Brooker, Malaria and helminth interactions in humans: an epidemiological viewpoint Annals of Tropical Medicine and Parasitology. ,vol. 100, pp. 551- 570 ,(2006) , 10.1179/136485906X118468
Million Getachew, Ketema Tafess, Ahmed Zeynudin, Delenesaw Yewhalaw, Prevalence Soil Transmitted Helminthiasis and malaria co-infection among pregnant women and risk factors in Gilgel Gibe dam Area, Southwest Ethiopia BMC Research Notes. ,vol. 6, pp. 263- 263 ,(2013) , 10.1186/1756-0500-6-263
Chukwuocha Uchechukwu Madukaku, Dozie Ikechukwu Nosike, Chukwuocha Adanna Nneoma, None, Malaria and its burden among pregnant women in parts of the Niger Delta area of Nigeria Asian Pacific Journal of Reproduction. ,vol. 1, pp. 147- 151 ,(2012) , 10.1016/S2305-0500(13)60066-4
Mathieu Nacher, Frederick Gay, Pratap Singhasivanon, Srivicha Krudsood, Sombat Treeprasertsuk, Dominique Mazier, Ioannis Vouldoukis, Sornchai Looareesuwan, Ascaris lumbricoides infection is associated with protection from cerebral malaria. Parasite Immunology. ,vol. 22, pp. 107- 113 ,(2000) , 10.1046/J.1365-3024.2000.00284.X