Is choline PET useful for identifying intraprostatic tumour lesions? A literature review.

作者: Joachim Chan , Isabel Syndikus , Shelan Mahmood , Lynn Bell , Sobhan Vinjamuri

DOI: 10.1097/MNM.0000000000000338

关键词:

摘要: More than 80% of patients with intermediate-risk or high-risk localized prostate cancer are cured radiation doses 74-78 Gy, but high increase the risk for late bowel and bladder toxicity among long-term survivors. Dose painting, defined as dose escalation to areas in containing tumour, rather whole gland, minimizes normal tissues hence toxicity. It requires accurate identification location size these lesions, which functional MRI is current gold standard. Many studies have assessed use choline PET staging newly diagnosed patients. This review will discuss important imaging variables affecting accuracy scans, how contributes tumour used radiotherapy planning can improve patient pathway involving radiotherapy. In summary, available literature shows that improves higher tracer delayed (although optimal uptake time unclear), by improved addition imaging. We propose future research prolonged multiphase imaging, may further accuracy.

参考文章(52)
Mohsen Beheshti, Athar Haroon, Jamshed B. Bomanji, Werner Langsteger, Fluorocholine PET/computed tomography: physiologic uptake, benign findings, and pitfalls. Pet Clinics. ,vol. 9, pp. 299- 306 ,(2014) , 10.1016/J.CPET.2014.03.001
Michael Pinkawa, Richard Holy, Marc D. Piroth, Jens Klotz, Sandra Nussen, Thomas Krohn, Felix M. Mottaghy, Martin Weibrecht, Michael J. Eble, Intensity-Modulated Radiotherapy for Prostate Cancer Implementing Molecular Imaging with 18F-Choline PET-CT to Define a Simultaneous Integrated Boost Strahlentherapie und Onkologie. ,vol. 186, pp. 600- 606 ,(2010) , 10.1007/S00066-010-2122-5
Sven Perner, Norbert M Blumstein, Sven N Reske, Frank Finsterbusch, Darius Kocot, Peter Möller, Bernd Neumaier, Hans-Werner Gottfried, Gerhard Glatting, Imaging Prostate Cancer with 11C-Choline PET/CT The Journal of Nuclear Medicine. ,vol. 47, pp. 1249- 1254 ,(2006)
Giuseppe Martorana, Romeo Canini, Mohsen Farsad, Barbara Corti, Roberto Franchi, Cinzia Pettinato, Cristina Nanni, Walter Grigioni, Nino Monetti, Riccardo Schiavina, Paolo Castellucci, Stefano Boschi, Stefano Fanti, Mario Marengo, Eugenio Salizzoni, Detection and localization of prostate cancer: correlation of (11)C-choline PET/CT with histopathologic step-section analysis. The Journal of Nuclear Medicine. ,vol. 46, pp. 1642- 1649 ,(2005)
Michael Pinkawa, Charbel Attieh, Marc D. Piroth, Richard Holy, Sandra Nussen, Jens Klotz, Robert Hawickhorst, Wolfgang Schäfer, Michael J. Eble, Dose-escalation using intensity-modulated radiotherapy for prostate cancer--evaluation of the dose distribution with and without 18F-choline PET-CT detected simultaneous integrated boost. Radiotherapy and Oncology. ,vol. 93, pp. 213- 219 ,(2009) , 10.1016/J.RADONC.2009.07.014
Sophia Rahman, Harry Cosmatos, Giatri Dave, Stephen Williams, Michael Tome, PREDICTING PELVIC LYMPH NODE INVOLVEMENT IN CURRENT-ERA PROSTATE CANCER International Journal of Radiation Oncology Biology Physics. ,vol. 82, pp. 906- 910 ,(2012) , 10.1016/J.IJROBP.2010.11.053
Johannes G. Korporaal, Cornelis A.T. van den Berg, Greetje Groenendaal, Maaike R. Moman, Marco van Vulpen, Uulke A. van der Heide, The use of probability maps to deal with the uncertainties in prostate cancer delineation. Radiotherapy and Oncology. ,vol. 94, pp. 168- 172 ,(2010) , 10.1016/J.RADONC.2009.12.023
S. Vinjamuri, J. Uzan, S. Riley, P.W. Mayles, PO-0847 18FLUORO-ETHYL CHOLINE PET CT FOR RADIOBIOLOGICALLY OPTIMISED PROSTATE DOSE-PAINTING (BIOPROP) Radiotherapy and Oncology. ,vol. 103, ,(2012) , 10.1016/S0167-8140(12)71180-5
Emilio Bria, Federica Cuppone, Diana Giannarelli, Michele Milella, Enzo Maria Ruggeri, Isabella Sperduti, Paola Pinnarò, Edmondo Terzoli, Francesco Cognetti, Paolo Carlini, Does hormone treatment added to radiotherapy improve outcome in locally advanced prostate cancer?: meta-analysis of randomized trials. Cancer. ,vol. 115, pp. 3446- 3456 ,(2009) , 10.1002/CNCR.24392
Greetje Groenendaal, Maaike R. Moman, Johannes G. Korporaal, Paul J. van Diest, Marco van Vulpen, Marielle E.P. Philippens, Uulke A. van der Heide, Validation of functional imaging with pathology for tumor delineation in the prostate Radiotherapy and Oncology. ,vol. 94, pp. 145- 150 ,(2009) , 10.1016/J.RADONC.2009.12.034