Is nephroureterectomy necessary in all cases of upper tract transitional cell carcinoma? Long-term results of conservative endourologic management of upper tract transitional cell carcinoma in individuals with a normal contralateral kidney.

作者: Daniel S Elliott , Joseph W Segura , Deborah Lightner , David E Patterson , Michael L Blute

DOI: 10.1016/S0090-4295(01)01109-8

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摘要: Abstract Objectives. To evaluate the endoscopic management of upper urinary tract transitional cell carcinoma (TCC) as a first-line treatment in patients with normal contralateral kidney. Methods. During an 11-year period, 21 diagnosed TCC were treated conservative endourologic techniques using either neodymium:yttrium-aluminum-garnet laser or electrocautery at our institution. The followed up for mean 6.1 years (range 1 to 11.6). Results. A total 8 renal pelvic tumors and 13 ureteral found. All Stage T1 less grade 3 less. than 2 cm greatest dimension 0.4 2). Of patients, 7 (33%) had one local recurrence (4.7%) developed two recurrences. tumors, 6 (46%) recurred; (12%) recurred. No recurrent tumor was shown have increase grade. target units, 17 (81%) preserved; 4 (19%) required nephroureterectomy because recurrence. Overall, 11 series died, 10 non-TCC etiology secondary invasive bladder that after TCC. died result their Conclusions. Endourologic is evolving field; however, properly selected can be safely effectively used

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