fMRI hippocampal activity during a virtual radial arm maze.

摘要: Numerous studies have shown that the hippocampus is critical for spatial memory. Within nonhuman research, a task often used to assess memory radial arm maze. Because of nature this task, maze function hippocampus. Our goal was extrapolate humans and examine whether healthy undergraduates utilize their while performing virtual reality version task. Thirteen performed during functional magnetic resonance imaging. The brain maps activity reveal bilateral hippocampal BOLD signal changes performance However, paradoxically, change decreases component Additionally, we note frontal cortex reflective working circuits. These data that, as predicted by rodent literature, involved in humans. Hence, may be integrity so predict risk or severity variety psychiatric disorders.