Inhibition of COX-2 expression by endocannabinoid 2-arachidonoylglycerol is mediated via PPAR-γ.
作者： Huizhi Du , Xiaolei Chen , Jian Zhang , Chu Chen
DOI: 10.1111/J.1476-5381.2011.01444.X
关键词:
摘要: … were pulled from borosilicate glass with a micropipette puller … by exogenous application of 2-AG (3 µM), consistent with our … of 2-AG or enhancement of endogenous 2-AG is mediated …
sci-hub.se 参考文章(73)
F Comelli, G Giagnoni, I Bettoni, M Colleoni, B Costa, The inhibition of monoacylglycerol lipase by URB602 showed an anti‐inflammatory and anti‐nociceptive effect in a murine model of acute inflammation British Journal of Pharmacology. ,vol. 152, pp. 787- 794 ,(2007) , 10.1038/SJ.BJP.0707425
Nan Sang, Jian Zhang, Chu Chen, PGE2 glycerol ester, a COX-2 oxidative metabolite of 2-arachidonoyl glycerol, modulates inhibitory synaptic transmission in mouse hippocampal neurons The Journal of Physiology. ,vol. 572, pp. 735- 745 ,(2006) , 10.1113/JPHYSIOL.2006.105569
Jin Jiang, Gary Struhl, Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb Nature. ,vol. 391, pp. 493- 496 ,(1998) , 10.1038/35154
Mercedes Ricote, Andrew C. Li, Timothy M. Willson, Carolyn J. Kelly, Christopher K. Glass, The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation Nature. ,vol. 391, pp. 79- 82 ,(1998) , 10.1038/34178
Chengyu Jiang, Adrian T. Ting, Brian Seed, PPAR-γ agonists inhibit production of monocyte inflammatory cytokines Nature. ,vol. 391, pp. 82- 86 ,(1998) , 10.1038/34184
A Lenman, C J Fowler, Interaction of ligands for the peroxisome proliferator‐activated receptor γ with the endocannabinoid system British Journal of Pharmacology. ,vol. 151, pp. 1343- 1351 ,(2007) , 10.1038/SJ.BJP.0707352
Guy A. Cabral, Steven J. Carlisle, John M. Olson, Yaakov Waksman, The Central Cannabinoid Receptor (CB1) Mediates Inhibition of Nitric Oxide Production by Rat Microglial Cells Journal of Pharmacology and Experimental Therapeutics. ,vol. 288, pp. 1357- 1366 ,(1999)
Yosef Sarne, Raphael Mechoulam, Cannabinoids: Between Neuroprotection and Neurotoxicity Current Drug Targets - Cns & Neurological Disorders. ,vol. 4, pp. 677- 684 ,(2005) , 10.2174/156800705774933005
Christopher K Glass, Kaoru Saijo, Beate Winner, Maria Carolina Marchetto, Fred H Gage, None, Mechanisms Underlying Inflammation in Neurodegeneration Cell. ,vol. 140, pp. 918- 934 ,(2010) , 10.1016/J.CELL.2010.02.016
Eun Jung Park, Soo Young Park, Eun-hye Joe, Ilo Jou, None, 15d-PGJ2and Rosiglitazone Suppress Janus Kinase-STAT Inflammatory Signaling through Induction of Suppressor of Cytokine Signaling 1 (SOCS1) and SOCS3 in Glia Journal of Biological Chemistry. ,vol. 278, pp. 14747- 14752 ,(2003) , 10.1074/JBC.M210819200