Late Changes Following Single Dose Roentgen Irradiation of Rat Small Intestine

作者: M. Hauer Jensen , T. Sauer , F. Devik , K. Nygaard

DOI: 10.3109/02841868309134045

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摘要: SUMMARY In female Wistar rats a 10 cm long exteriorized mid small intestinal segment was roentgen irradiated with 17, 19, 21 and 23 Gy as single exposures. Animals were killed in groups of 3 at intervals 6 weeks from 2 to 50 following irradiation. Irradiation injury assessed us- ing 8 macroscopic histopathologic parameters, an score for each animal calculated. The param- eters used divided subgroups, early late alterations, showing different types development. the alterations decreased 20 irradiation then remained constant. increased seemed stabilize about fotlowing After initial there no progression injury. ACKNOWLEDGEMENTS Valuable advice S. Hagen A. Serck-Hanssen is gratefully acknowledged. This investigation sup- ported by grants Norwegian Society Fighting Cancer.

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