Cribra orbitalia in the ancient Nile Valley and its connection to malaria.

摘要: Cribra orbitalia is a common skeletal lesion found on ancient human remains excavated from the Nile Valley. Recent etiological research implicates hemolytic anemia as main factor leading to formation of cribra orbitalia. Further, an association between caused by malaria and has been demonstrated. The presence in Valley verified directly through genetic immunologic studies Egyptian mummies, but its prevalence spread remain unknown. As some models have pointed pathway malarial dispersion during Dynastic period, variability rates should provide way track disease spread. This study surveyed frequencies at 29 sites, representing 4760 individuals ranging prehistoric Christian periods situated 3rd Cataract Delta. Results showed high rates, with overall mean 42.8% total population affected. Over time space, data no significant correlation, suggesting levels affected equally late pre-dynastic periods. These findings suggest widespread endemic before Egypt.