Speckle-Tracking Echocardiographic Measures of Right Ventricular Function Correlate With Improvement in Exercise Function After Percutaneous Pulmonary Valve Implantation.

摘要: Background Speckle-tracking echocardiographic (STE) measures of right ventricular (RV) function appear to improve after transcatheter pulmonary valve implantation (TPVI). Measures exercise function, such as ventilatory efficiency (the minute ventilation [V E ]/carbon dioxide production [Vco 2 ] slope), have been shown be prognostic mortality in patients who may require TPVI. The aim this study was evaluate the correlation between STE RV and changes V /Vco Methods echocardiography cardiopulmonary testing were performed at baseline 6 months TPVI 24 from four centers. Conventional also assessed. Echocardiographic stress test results interpreted by single blinded observers separate core laboratories. Results All demonstrated relief regurgitation stenosis Improvements longitudinal strain (−16.9 ± 3.5% vs −19.7 ± 4.3%, P −1 , slope improved (32.4 ± 5.7 31.5 ± 8.8,  = .03). No other significant or found. On multivariate regression, change independently associated with early diastolic rate ( r  = −0.60, Conclusions hold potential for use predictors outcomes requiring Future studies should directly assess significance population.