Role of H2RA and Proton Pump Inhibitor Therapy in Treating Reflux Disease

摘要: H2-receptor antagonists (H2RAs) and proton pump inhibitors (PPIs) are the primary classes of medication prescribed to treat gastroesophageal reflux disease (GERD) patients. While these medications can be used alone or in combination, PPIs demonstrate superior symptom control healing esophagitis. They also play an important role management patients with nonerosive disease, nocturnal reflux, Barrett’s esophagus, peptic strictures, extraesophageal disease. Both safe well tolerated, a low risk adverse events. However, often overused should selectively reserved for severe complications GERD intractable symptoms. Patients milder symptoms may treated H2RAs antacids.