Lipase inhibitory activity of chlorophyll a, isofucosterol and saringosterol isolated from chloroform fraction of Sargassum thunbergii.
作者： Koth-Bong-Woo-Ri Kim , Min-Ji Kim , Dong-Hyun Ahn
DOI: 10.1080/14786419.2014.900769
关键词:
摘要: Three compounds (chlorophyll a, isofucosterol and saringosterol) were isolated from chloroform fraction of Sargassum thunbergii extract. The three had two- to fourfold lower lipase inhibitory activity than that the CHCl3:MeOH (C:M) (100:1) (fraction I, 83.78% at 1 mg/mL). These results suggested high I was attributable actions compounds. Therefore, S. has potential for application as an anti-obesity agent.
sci-hub.se 参考文章(12)
M. Abdel-Mogib, M. E. El-Naggar, M. E. Mostafa, A. A. M. Dawidar, Acaricidal activity and chemical constituents of Hyoscyamus muticus against Teteranychus urticae Koch. Revista Latinoamericana de Química. ,vol. 37, pp. 45- 55 ,(2009)
Sung-Hwan Eom, Myung-Suk Lee, Eun-Woo Lee, Young-Mog Kim, Tae Hoon Kim, Pancreatic lipase inhibitory activity of phlorotannins isolated from Eisenia bicyclis. Phytotherapy Research. ,vol. 27, pp. 148- 151 ,(2013) , 10.1002/PTR.4694
So-Young Lee, Eu-Jin Song, Koth-Bong-Woo-Ri Kim, So-Young Yoon, Seo-Jin Kim, So-Jeong Lee, Yong-Ki Hong, Sung-Mee Lim, Dong-Hyun Ahn, 지충이(Sargassum thunbergii) 에탄올 추출물의 항균활성 Journal of The Korean Society of Food Science and Nutrition. ,vol. 38, pp. 502- 508 ,(2009) , 10.3746/JKFN.2009.38.4.502
Megumi Matsumoto, Masashi Hosokawa, Noriko Matsukawa, Masahito Hagio, Aki Shinoki, Megumi Nishimukai, Kazuo Miyashita, Takaji Yajima, Hiroshi Hara, Suppressive effects of the marine carotenoids, fucoxanthin and fucoxanthinol on triglyceride absorption in lymph duct-cannulated rats European Journal of Nutrition. ,vol. 49, pp. 243- 249 ,(2010) , 10.1007/S00394-009-0078-Y
Robert A. Moreau, Bruce D. Whitaker, Kevin B. Hicks, Phytosterols, phytostanols, and their conjugates in foods: structural diversity, quantitative analysis, and health-promoting uses Progress in Lipid Research. ,vol. 41, pp. 457- 500 ,(2002) , 10.1016/S0163-7827(02)00006-1
Anne Ballinger, Steven R Peikin, Orlistat: its current status as an anti-obesity drug European Journal of Pharmacology. ,vol. 440, pp. 109- 117 ,(2002) , 10.1016/S0014-2999(02)01422-X
Gleen W. Patterson, Sterols of Laminaria Comparative Biochemistry and Physiology. ,vol. 24, pp. 501- 505 ,(1968) , 10.1016/0010-406X(68)91001-3
Karen M. Hvizdos, Anthony Markham, Orlistat: a review of its use in the management of obesity. Drugs. ,vol. 58, pp. 743- 760 ,(1999) , 10.2165/00003495-199958040-00015
El Sayed H. El Ashry, Atta-ur-Rahman, M. Iqbal Choudhary, Sherif H. Kandil, Ahmed El Nemr, Tahsin Gulzar, Aida H. Shobier, Studies on the constituents of the green alga Ulva lactuca Chemistry of Natural Compounds. ,vol. 47, pp. 335- 338 ,(2011) , 10.1007/S10600-011-9926-0
Seif-Eldin N. Ayyad, Salah Z. A Sowellim, Mohamed S. El-Hosini, Amal Abo-Atia, The structural determination of a new steroidal metabolite from the brown alga Sargassum asperifolium. Zeitschrift für Naturforschung C. ,vol. 58, pp. 333- 336 ,(2003) , 10.1515/ZNC-2003-5-607